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You are here:Home » Antibodies » Abs to Ion Channel » Anti -OATP (Organic anion transporting polypeptide)

Anti -OATP (Organic anion transporting polypeptide)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic anions from the blood by a process called "renal secretion". Besides kidney, anionic substrates are also transported in other organs, e.g., choroid plexus, eye, airway, and placenta. Several multispecific OATs (OAT1-3, OAT-K1 and OATK2) and OATPs (organic anion transporting polypeptides; oatp1-3, LST-1, and PGT), have been cloned and characterized from various tissues. OATPs family of proteins share significant sequence homology, and general secondary protein structure (up to 12 transmembrane domains with cytoplasmic N and C-terminus).
Catalog #O3003-29
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-10ug/ml using ECL.
ELISA: 0.5-1ug/ml. Control peptide can be used to coat plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.
Recommended Control PeptideO3003: OATP, Human, Control Peptide (Organic anion transporting polypeptide)
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% BSA.
PurityPurified by affinity chromatography.
ImmunogenA 15aa peptide internal sequence (middle regions) of human OATP (KLH). Epitope
SpecificityRecognizes human OATP. No significant sequence homology is detected with other oatp1-3 or human LST-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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