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You are here:Home » Biochemicals » Biochem-Antibiotics » Ochratoxin B

Ochratoxin B

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Specifications

Ochratoxin B is the non-chlorinated analogue of the much more extensively studied ochratoxin A. It is co-produced by the same species of Aspergillus and Penicillium that are associated with food spoilage. Ochratoxin B has received little focused investigation and its mode of action and potential hazards have been inferred from ochratoxin A. Ochratoxin A and B often produced by the Aspergillus species and the Penicilium species are routinely detected with rapid tests (e.g. ELISA) and reference methods (chromatography, e.g. LC-FLD or LC-MS/MS).
Catalog #O5305-04
Source Aspergillus ochraceus MST-FP2005
CAS Name (R)-N-[(3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl)carbonyl]-L-phenylalanine
Synonyms N-[[(3R)-3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl]carbonyl]-L-phenylalanine; N-[(8-Hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl]-3-phenyl-L- alanine; (R)-N-[(3,4-Dihydro-8-hydroxy-3-methyl-1-oxo-1H-2-benzopyran-7-yl) carbonyl]-L-phenylalanine
Apperance Pale yellow solid
Solubility: Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Percent Composition C 65.03%, H 5.18%, N 3.79%, O 25.99%
Properties: The less toxic dechloro deriv of ochratoxin A. Crystals from methanol, mp 221° (van der Merwe); also reported as 208-209° (Nesheim). Exhibits blue fluorescence. [a]D -35° (c = 0.15 in ethanol). uv max: 218, 318 nm (e 37200, 6900).
Melting Point: mp 221° (van der Merwe)
Optical Rotation: [a]D -35° (c = 0.15 in ethanol)
Absorption maximum: uv max: 218, 318 nm (e 37200, 6900)
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number4825-86-9
Molecular FormulaC20H19NO6
Molecular Weight369.37
UN NumberUN 3462, Class 6.1, Packing group III
Risk Statements22-36/37/38-65-48/23/24/25-36/38-11-46-45
Safety Statements26-36-45-16-53
RTECSAY6825000
WGK Germany3
SourceAspergillus ochraceus MST-FP2005
Purity~99%
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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