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Oligomycin A
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| Oligomycin A is the dominant analogue of a class macrocyclic lactones isolated from selected strains of Streptomyces sp. Oligomycin A is a inhibitor of mitochondrial F1F0-ATPase. Induces apoptosis in a variety of cell types. Makes cells more susceptible to cell death and also leads to a switch in the death mode from apoptosis to necrosis. Oligomycin exibits a broad biological profile including antifungal, antitumor and nematocidal activities. | | | Catalog # | O6154 | | Purity | >95% by HPLC | | Solubility | Soluble in ethanol, methanol, DMF or DMSO. | | Related to | Oligomycin B, Oligomycin C, 21-hydroxyoligomycin A | | CAS Number | 579-13-5 | | Molecular Formula | C45H74O11 | | Molecular Weight | 791.1 | | Source | Streptomyces sp. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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