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Abs to Extracellular Matrix Proteins
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Anti -Olfactomedin 4 (OLFM4, Olfactomedin-4, OLM4, Antiapoptotic Protein GW112, hGC-1, G-CSF-stimulated Clone 1 Protein, hOLfD, GW112, UNQ362/PRO698)
Anti -Olfactomedin 4 (OLFM4, Olfactomedin-4, OLM4, Antiapoptotic Protein GW112, hGC-1,
G-CSF-stimulated Clone 1 Protein, hOLfD, GW112, UNQ362/PRO698)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| OLFM4 is a 510aa extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2:M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion. | | | Catalog # | O6170-12 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.5-3ug/ml | | Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to amino acids 400-419 (YVYNDGYLLNYDLSVLQKPQ) of human Olfactomedin 4, Gen Bank. gb|AAH47740.1| | | Specificity | Recognizes human Olfactomedin 4. Species Crossreactivity | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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