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You are here:Home » Antibodies » Abs to Enzymes, Protease (Proteinase, Peptidase) » Anti -Omi, HtrA2 (HtrA Serine Peptidase 2, High Temperature Requirement Protein A2, HtrA-like Serine Protease, Omi Stress-regulated Endoprotease, PARK13, Protease Serine 25, PRSS25, Serine Protease 25, Serine Protease HtrA2 Mitochondrial, Serine Protease Omi)

Anti -Omi, HtrA2 (HtrA Serine Peptidase 2, High Temperature Requirement Protein A2,
HtrA-like Serine Protease, Omi Stress-regulated Endoprotease, PARK13, Protease Serine 25,
PRSS25, Serine Protease 25, Serine Protease HtrA2 Mitochondrial, Serine Protease Omi)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B IP IH IC FC
HtrA2 (Omi) is a serine protease that plays a significant role in apoptosis. Localized to the intermembrane space of the mitochondria, HtrA2 exists as at least four isoforms (1). In response to cellular stress signals, HtrA2 is released into the cytosol. HtrA2 induces cell death either by
direct binding to BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC-inhibition-independent caspase-independent and serine protease activity-dependent mechanism (2,3).
Catalog #O6350-05D
ApplicationsSuitable for use in Flow Cytometry, Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:70
Western Blot: 1:500-1:5000
Immunoprecipitation: 1:10
Immunohistochemistry: 1:100-1:250
Immunocytochemistry: 1:250-1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No9H492
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 50mM Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% BSA, 0.01% sodium azide, 40% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues on human HtrA2 (O43464).
SpecificityRecognizes human HtrA2. Species Crossreactivity: Mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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