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You are here:Home » Antibodies » Abs to Opioid Receptors, Agonists » Anti -Opioid Receptor, delta, CT, aa360-372

Anti -Opioid Receptor, delta, CT, aa360-372

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum E B IH
The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Catalog #O7030-10
ApplicationsSuitable for ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionImmunohistochemistry (ABC): 1:800 Stains specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor.
Western Blot: 1:800; Band at ~55kD is observed using whole rat brain homogenate.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, 10mg/ml BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA.
PuritySerum
ImmunogenSynthetic peptide corresponding to the carboxyl terminal of human delta opioid receptor covalently attached to a carrier protein.
SpecificityRecognizes human Delta Opioid Receptor (360-372)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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