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Anti -Opioid Receptor, delta, CT, aa360-372
Anti -Opioid Receptor, delta, CT, aa360-372
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
E B IH |
|
| The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities. | | | Catalog # | O7030-10 | | Applications | Suitable for ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested. | | Recommended Dilution | Immunohistochemistry (ABC): 1:800 Stains specific cells in various regions of PLP fixed rat brain sections known to express the delta opioid receptor. | | Western Blot: 1:800; Band at ~55kD is observed using whole rat brain homogenate. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, 10mg/ml BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA. | | Purity | Serum | | Immunogen | Synthetic peptide corresponding to the carboxyl terminal of human delta opioid receptor covalently attached to a carrier protein. | | Specificity | Recognizes human Delta Opioid Receptor (360-372) | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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