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Specifications

Clone Host Grade Applications Polyclonal Rabbit Serum IH

The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Catalog #	O7030-13
Applications	Suitable for use in Immunohistochemistry. Other applications not tested.
Recommended Dilution	Immunohistochemistry: 1:1000. CNS tissues fixed in PLP. Can be used with paraffin embedded tissue also.
	Optimal dilutions to be determined by the researcher.
Control Peptide	O7030-12: Opioid Receptor, delta, NT, Control Peptide
Storage and Stability	May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Number	n/a
Clone Type	Polyclonal
Isotype	IgG
Host	Rabbit
Source	Mouse
Concentration	Not Determined
Form	Supplied as a liquid.
Purity	Serum
Immunogen	Delta opioid receptor N-terminal peptide, LVPSARAELQSSPLV.
Specificity	Recognizes mouse Delta opioid receptor.
Species Crossreactivity	Rat.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.