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Anti -Opioid Receptor, mu (CT) (aa391-398)
Anti -Opioid Receptor, mu (CT) (aa391-398)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Serum |
B IC |
|
| Opioid receptors are G-protein coupled receptors. Most actions of exogenous opioids, such as morphine, are mediated through the mu-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidyl-inositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities. | | | Catalog # | O7030-35A | | Applications | Suitable for Immunocytochemistry and Western Blot. Other applications have not been tested. | | Recommended Dilution | Immunocytochemistry: 1:2,000 | | Western Blot: 1:500 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA. | | Purity | Serum | | Immunogen | Peptide analogue of the carboxyl terminal of the mu opioid receptor covalently attached to a carrier protein. | | Specificity | Recognizes the mu opioid receptor (ct) (aa391-398). Crossreactivity: Mu Opioid Receptor (391-398) 100%, Mu Opioid Receptor ~50%, Delta Opioid Receptor (360-371) 0%, Delta Opioid Receptor 0%, Kappa Opioid Receptor (346-380) 0%, Kappa Opioid Receptor 0%. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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