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You are here:Home » Antibodies » Abs to Opioid Receptors, Agonists » Anti -Opioid Receptor, mu (CT) (aa391-398)

Anti -Opioid Receptor, mu (CT) (aa391-398)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IC
Opioid receptors are G-protein coupled receptors. Most actions of exogenous opioids, such as morphine, are mediated through the mu-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidyl-inositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Catalog #O7030-35A
ApplicationsSuitable for Immunocytochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionImmunocytochemistry: 1:2,000
Western Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a lyophilized powder. Reconstitute with 100ul sterile PBS, 10mg/ml BSA.
PuritySerum
ImmunogenPeptide analogue of the carboxyl terminal of the mu opioid receptor covalently attached to a carrier protein.
SpecificityRecognizes the mu opioid receptor (ct) (aa391-398). Crossreactivity: Mu Opioid Receptor (391-398) 100%, Mu Opioid Receptor ~50%, Delta Opioid Receptor (360-371) 0%, Delta Opioid Receptor 0%, Kappa Opioid Receptor (346-380) 0%, Kappa Opioid Receptor 0%.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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