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You are here:Home » Antibodies » Abs to Opioid Receptors, Agonists » Anti -Opioid Receptor, mu (KIAA0403, Mu Type Opioid Receptor, MOR, muOR, Mu Type Opioid Receptor MOR-1, MOR1, MOR-1, Opioid Receptor mu, OPRM, Opioid Receptor mu-1, OPRM1)

Anti -Opioid Receptor, mu (KIAA0403, Mu Type Opioid Receptor, MOR, muOR, Mu Type Opioid
Receptor MOR-1, MOR1, MOR-1, Opioid Receptor mu, OPRM, Opioid Receptor mu-1, OPRM1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Serum B IH IC
Most actions of exogenous opioids, such as morphine, are mediated through the mu-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidyl-inositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Catalog #O7030-36A
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Immunohistochemistry: 1:1250-1:2500
Immunocytochemistry: 1:1250-1:2500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
ConcentrationNot determined
FormSupplied as a liquid in PBS, 0.05% sodium azide, before the addition of glycerol to 40%.
PurityNeat serum
ImmunogenSynthetic peptide corresponding to aa384-398 (NHQLENLEAETAPLP) of the C-terminus of the rat Opioid Receptor, mu.
SpecificityRecognizes Mu opioid receptor, C-terminal domain.
Species CrosseactivityRat, mouse, primate and human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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