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You are here:Home » Antibodies » Abs to Opioid Receptors, Agonists » Anti -Opioid Receptor, mu, Internal (MOR1)

Anti -Opioid Receptor, mu, Internal (MOR1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Most actions of exogenous opioids, such as morphine, are mediated through the mu-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidyl-inositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.
Catalog #O7030-42
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlRat brain lysates.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
ConcentrationNot determined.
FormSupplied as a liquid in Dulbeccos phosphate buffered saline, pH 7.4. 1mg/ml BSA, 0.05% sodium azide, 50% glycerol,.
PurityPurified by affinity chromatography.
ImmunogenPeptide derived from internal region of the human mu-opioid receptor.
SpecificityRecognizes the mu-opioid receptor. Species sequence homology: rat (88%), mouse (94%). human (100%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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