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O8053-02A Goat Anti-OSCAR (Osteoclast-associated Immunoglobulin-like Receptor, Osteoclast-associated Receptor, hOSCAR, Polymeric Immunoglobulin Receptor 3, PIgR-3, PIgR3, Poly-Ig Receptor 3)

Specifications
References
Clone Type
Polyclonal
Host
Goat
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E
Crossreactivity
Hu
Accession #
NP_996554.1
Gene ID
126014
Shipping Temp
Blue Ice
Storage Temp
-20°C

Recently, a novel member of the leukocyte receptor complex (LRC)-encoded family has been identified that is expressed specifically in osteoclast (OC). This protein named as OC-associated receptor (OSCAR) play critical roles in the regulation of both innate and adaptive immune responses and bone-specific regulator of OC differentiation.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to C-EGPEARPASSAP, from OSCAR, at the internal region of the protein (NP_996554.1).
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes OSCAR. Species sequence homology: Human.
References
1. Kim K, Kim JH, Lee J, Jin HM, Lee SH, Fisher DE, Kook H, Kim KK, Choi Y, Kim N. Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. J Biol Chem. 2005 Oct 21;280(42):35209-16. Epub 2005 Aug 18.
USBio References
No references available
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