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You are here:Home » Antibodies » Abs to Osteopontin » Anti -Osteopontin, CT (OPN, Bone Sialoprotein I, BSP-1, Secreted Phosphoprotein 1, SPP1, Urinary Stone Protein, Nephropontin, Uropontin, SPP-1, BNSP, PSEC0156)

Anti -Osteopontin, CT (OPN, Bone Sialoprotein I, BSP-1, Secreted Phosphoprotein 1, SPP1,
Urinary Stone Protein, Nephropontin, Uropontin, SPP-1, BNSP, PSEC0156)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Osteopontin is an acid-rich, multidomain, phosphorylated 60kD glycoprotein. Osteopontin is a secreted chemokine-like protein that is a member of the SIBLING family, and is synthesized by many cell types. Osteopontin is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteoponitn is also thought to be important to cell-matrix interaction, and can bind fibronectin, collagen and calcium. Osteopontin has been suggested to have a role in atherosclerosis, bone remodelling, angiogenesis, wound healing and tissue injuries.
Catalog #O8064-06N
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:64000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-DPKSKEEDKHLK, from the C-terminal of osteopontin.
SpecificityRecognizes an epitope within the C-terminal region of osteopontin. Species sequence homology: canine, rat, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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