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You are here:Home » Biochemicals » Biochem-Antibiotics » 7-Oxostaurosporine (Antibiotic BMY 41950, Antibiotic RK 1409)

7-Oxostaurosporine (Antibiotic BMY 41950, Antibiotic RK 1409)


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7-Oxostaurosporine is the oxidised and highly fluorescent analogue of Antibiotics UCN-01 and UCN-02. 7-Oxostaurosporine is a potent inhibitor of protein kinase C and formation of cellular blebs induced by phorbols. It inhibits the cell cycle at the G2 stage with the accumulation of 4C DNA cells and possesses comparable activity against tumor cells lines to Antibiotic UCN-01. Despite its close relationship to Antibiotic UCN-01 and staurosporine, limited access to the metabolite has restricted a more complete investigation of its properties.
Catalog #O8238-40
DMSO, DMF, methanol and ethanol. Limited water solubility
CAS Number141196-69-2
Molecular FormulaC28H24N4O4
Molecular Weight480.52199999999999136
SourceStreptomyces sp.
Purity> 98% by HPLC
FormYellow solid
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesAntibiotic BMY 41950, Antibiotic RK 1409

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