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You are here:Home » Antibodies » Abs to Mitochondrial Proteins » Anti -PARL, NT (Presenilins-associated Rhomboid-like Protein, Mitochondrial, Mitochondrial Intramembrane Cleaving Protease PARL, PSARL, PRO2207)

Anti -PARL, NT (Presenilins-associated Rhomboid-like Protein, Mitochondrial, Mitochondrial
Intramembrane Cleaving Protease PARL, PSARL, PRO2207)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals By similarity. Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
Catalog #P0854-01B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa15 in human PARL at N-terminal conjugated to KLH.
SpecificityRecognizes human PARL. Species sequence homology: Mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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