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Abs to Tumor Suppressors
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Anti -p53 (Tumor Protein p53, Tumor Suppressor p53, TP53, TRP53, Cellular Tumor Antigen p53, Phosphoprotein p53, Antigen NY-CO-13, LFS1)
Anti -p53 (Tumor Protein p53, Tumor Suppressor p53, TP53, TRP53, Cellular Tumor Antigen
p53, Phosphoprotein p53, Antigen NY-CO-13, LFS1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rabbit |
Supernatant |
IH |
|
| p53 protein is crucial to normal regulation of cell growth and is a suppressor of tumor cell proliferation. The gene encoding for p53 is located on chromosome 17p, a frequent site of allelic loss in many tumors. A high proportion of breast and colon carcinomas are positive for p53 and this expression correlates with poor prognosis in breast cancer. This antibody recog- nizes both wild type and mutant forms of p53 protein under denaturing and non-denaturing conditions. | | | Catalog # | P1001-26F | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:50-1:100 for 30 mins. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | A high percentage of breast and colonic carcinomas show labeling for p53 protein (nuclear staining pattern) | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG | | Clone No | SP5 | | Host | Rabbit | | Source | Human | | Concentration | Not determined | | Form | Supplied as a liquid in 15mM sodium azide. | | Purity | Supernatant | | Immunogen | Recombinant protein corresponding to full length human wild type p53 protein. | | Specificity | Recognizes human p53 Protein. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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