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You are here:Home » Antibodies » Abs to Enzymes, Acetyltransferase » Anti -E1A Binding Protein p300 (EP300, Histone acetyltransferase p300, KAT3B, p300, P300, p300 HAT)

Anti -E1A Binding Protein p300 (EP300, Histone acetyltransferase p300, KAT3B, p300, P300,
p300 HAT)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH IF
E1A binding protein p300 is an E1A-associated cellular p300 transcriptional co-activator protein. It is related by sequence to CBP (CREB-binding protein [CREB: cyclic-AMP responsive element binding protein]), and like CBP can stimulate transcription through activation of CREB. E1A binding protein p300 activity is specifically inhibited by the adenovirus oncoprotein E1A. It has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF.
Catalog #P1010-04
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 10ug/ml
Immunohistochemistry: 3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, ddH2O. Reconstituted product is stable for 12 months at -20°C. Aliquot and store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No9G412
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a lyophilized powder in PBS, pH 7.2. Reconstitute with 50ul sterile ddH2O.
PurityPurified by affinity chromatography.
ImmunogenPartial recombinant protein of human E1A binding protein (aa731-830) with a GST tag.
SpecificityRecognizes human E1A binding protein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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