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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -PIAS4, CT (E3 SUMO-protein Ligase PIAS4, Protein Inhibitor of Activated STAT Protein 4, Protein Inhibitor of Activated STAT Protein gamma, PIAS-gamma, PIASy, PIASG)

Anti -PIAS4, CT (E3 SUMO-protein Ligase PIAS4, Protein Inhibitor of Activated STAT Protein
4, Protein Inhibitor of Activated STAT Protein gamma, PIAS-gamma, PIASy, PIASG)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation.
Catalog #P2150-09
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Western Blot: 1:100-1:500
Immunohistochemistry: 1:50-1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide selected from the C-terminal region of human PIASy1 (KLH).
SpecificityRecognizes human PIASy1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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