Anti -Palladin (PALLD, Cytoskeletal associated protein, CGI-151, FLJ22190, FLJ38193,
FLJ39139, KIAA0992, PNCA1, Sarcoma antigen NY-SAR-77, SIH002)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Sheep |
Affinity Purified |
B |
|
| Palladin (a cytoarchitectural protein named after the 16 century Venetian architect Palladio) is a cytoplasmic member of the myotilin/palladin family of proteins. Palladin is widely expressed and interacts with actin-associated proteins, thus promoting actin bundle stability. Human Palladin is 1383 amino acids (aa) in length and contains five I-type Ig-like domains (aa 271-360; 440-539; 1001-1085; 1135-1226; 1233-1324), a Pro-rich region (aa 634-864) and nine potential Ser/Thr phosphorylation sites. Multiple isoform variants exist. Predominant are a 140kD and 92-95kD short form that show alternative start sites at Met383 and Met712, respectively. The 140kD isoform also shows a deletion of aa 656-879 to generate an approximately 115kD isoform. | | | Catalog # | P2814-40 | | Apoplications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilutions | Western Blot: 0.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS. Aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Sheep | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophillized power in PBS, 5% Trehalose. Reconstitute with sterile 40-50% glycerol, PBS, 0.02% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | E. coli-derived rhPalladin (aa 1154-1304) | | Specificity | Recognizes human Palladin isoforms at 95, 115 and 140kD using Western blots. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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