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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -PANX2 (Pannexin2)

Anti -PANX2 (Pannexin2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Catalog #P3075
Function Structural component of the gap junctions.
Subunit Forms heteromeric channels with PANX1. Does not form homomeric channels (By similarity).
Gi# 163659920
NCBI Acc#: NP_443071.2
Swiss Prot Acc#: Q96RD6
Gene Name: PANX
Length (aa): 677
Mol. Weight: 69478D
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended DilutionELISA: 1:60,000 (titer)
Immunohistochemistry (paraffin): 4-8ug/ml
Western Blot: 1.25ug/ml
Optimal dilution to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~2mg/ml (after reconstitution)
FormSupplied as a powder lyophilized from a solution containing PBS with 2% sucrose. Reconstitute with 50ul sterile ddH2O or sterile 40-50% glycerol for long-term storage.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to a region of Human PANX2
SpecificityRecognizes human PANX2. Species Crossreactivity: mouse, rat, canine and zebra fish.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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