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You are here:Home » Antibodies » Abs to Ubiquitin Ligases » Anti -Parkin (AR-JP, E3 Ubiquitin Protein Ligase Parkin, FRA6E, LPRS2, Parkinson Disease (Autosomal Recessive, Juvenile) 2, Parkinson Disease Protein 2, Parkinson Juvenile Disease Protein 2, PARK2, PRKN 2, PRKN, PDJ, RING-type E3 Ubiquitin-protein Ligase, Ubiqu

Anti -Parkin (AR-JP, E3 Ubiquitin Protein Ligase Parkin, FRA6E, LPRS2, Parkinson Disease
(Autosomal Recessive, Juvenile) 2, Parkinson Disease Protein 2, Parkinson Juvenile Disease
Protein 2, PARK2, PRKN 2, PRKN, PDJ, RING-type E3 Ubiquitin-protein Ligase, Ubiqu

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Parkin (MW 50-58kD) has been mapped to chromosome 6 and encodes a protein of 465aa with similarity to ubiquitin at the amino terminus and a RING finger motif at the carboxyl terminus. Parkinsonís disease is the second most common neurodegenerative disease following Alzheimerís. The characteristic movement disorder results from dysfunction and neuron loss in the substantia nigra. Deletions in parkin, have been associated with autosomal-recessive juvenile parkinsonism.
Catalog #P3111-01A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:30 for 10min at RT
Staining of formalin-fixed tissues requires boiling tissues sections in 10mM citrate buffer, pH 6.0, for 10min followed by cooling at RT for 20min
Optimal dilutions to be determined by the researcher.
Positive ControlBrain
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the N-terminus of human Parkin.
SpecificityRecognizes human Parkin. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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