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You are here:Home » Antibodies » Abs to Calcium Binding Proteins » Anti -Parvalbumin (PVALB, Parvalbumin alpha, D22S749)

Anti -Parvalbumin (PVALB, Parvalbumin alpha, D22S749)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant IH
Alpha parvalbumin is a water-soluble calcium-binding protein found in select fast-spiking inhibitory GABAergic interneurons with a calcium buffering capacity. Neurons that contain parvalbumin seem to be resistant to ischaemia, epilepsy and N-methyl-D-aspartate receptor agonists due to their ability to buffer increases in intracellular albumin. Reduced expression of alpha parvalbumin has been reported in Purkinje cells in cases of spinocerebellar ataxia-1. This antibody is specific for the alpha form of parvalbumin.
Catalog #P3113-50A
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 1:200-1:400 for 1 hr. at RT
Optimal dilutions to be determined by the researcher.
Positive Control
Cerebellum (cytoplasmic and nuclear staining pattern)
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No2E11
HostMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O.
PuritySupernatant
ImmunogenRecombinant fusion protein representing most of the parvalbumin alpha molecule.
SpecificityRecognizes Paravalbumin. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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