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Abs to Calcium Binding Proteins
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Anti -Parvalbumin (PVALB, Parvalbumin alpha, D22S749)
Anti -Parvalbumin (PVALB, Parvalbumin alpha, D22S749)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
IH |
|
| Alpha parvalbumin is a water-soluble calcium-binding protein found in select fast-spiking inhibitory GABAergic interneurons with a calcium buffering capacity. Neurons that contain parvalbumin seem to be resistant to ischaemia, epilepsy and N-methyl-D-aspartate receptor agonists due to their ability to buffer increases in intracellular albumin. Reduced expression of alpha parvalbumin has been reported in Purkinje cells in cases of spinocerebellar ataxia-1. This antibody is specific for the alpha form of parvalbumin. | | | Catalog # | P3113-50A | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 1:200-1:400 for 1 hr. at RT | | Optimal dilutions to be determined by the researcher. | | Positive Control | | | Cerebellum (cytoplasmic and nuclear staining pattern) | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2E11 | | Host | Mouse | | Concentration | Not determined | | Form | Supplied as a lyophilized powder in 15mM sodium azide. Reconstitute with 1ml dH2O. | | Purity | Supernatant | | Immunogen | Recombinant fusion protein representing most of the parvalbumin alpha molecule. | | Specificity | Recognizes Paravalbumin. Species Crossreactivity: Human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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