Anti -Patched 1 (PTCH, PTC, BCNS, FLJ42602, Holoprosencephaly 7, HPE7, NBCCS, Patched 1,
Patched Homolog 1, Patched Protein Homolog 1, PTC1, PTCH1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| Protein patched homolog 1 is a receptor for sonic hedgehog, a member of the hedgehog family of cell signaling proteins. Hedgehog signaling is regulated by Protein patched homolog 1 which keeps the pathway turned off in the absences of activation. This inhibits the function of associated downstream network components such as Smoothened (Smo). | | | Catalog # | P3113-82C4 | | Applications | Suitable for use in Western Blot and Immunohistochemistry. | | Other applications not tested. | | Recommended Dilutions | Western Blot: 0.1ug/ml detected Patched on 10ug of human skeletal muscle, fetal tissue lysate. | | Immunohistochemistry (Paraffin): 1:300 detected Patched in kidney tissue. Heat induced epitope retrieval with citrate buffer, pH 6.0 is recommended. | | Optimal dilutions to be determined by the researcher. | | Recommended Secondary Antibodies | I1904-39: IgG, X-Adsorbed (HRP) Pab Gt xRb | | I1904-40A: IgG, H&L, X-Adsorbed (HRP) Pab Gt xRb | | I1904-46Q: IgG, H&L (HRP) Pab Gt xRb | | Positive Control | Human skeletal muscle, fetal tissue lysate. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide. | | Purity | Purified by affinity chromatography. | | Immunogen | Linear peptide corresponding to the cytoplasmic domain of human Protein patched homolog 1, conjugated to KLH. | | (Accession #NP_000255) | | Specificity | Recognizes human Protein patched homolog 1 at ~160kD. Species Crossreactivity: mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -Patched 1 (PTCH, PTC, BCNS, FLJ42602, Holoprosencephaly 7, HPE7, NBCCS, Patched 1, Patched Homolog 1, Patched Protein Homolog 1, PTC1, PTCH1) |
External Links
|
