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You are here:Home » Antibodies » Abs to Tumor Suppressors » Anti -Patched, NT (PTCH, PTC, BCNS, FLJ42602, FLJ26746, Holoprosencephaly 7, HPE7, NBCCS, Patched 1, Patched Homolog 1, Protein Patched Homolog 1, PTC1, PTCH1, PTCH11)

Anti -Patched, NT (PTCH, PTC, BCNS, FLJ42602, FLJ26746, Holoprosencephaly 7, HPE7, NBCCS,
Patched 1, Patched Homolog 1, Protein Patched Homolog 1, PTC1, PTCH1, PTCH11)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E IH
Ptch a member of the patched gene family. This protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. It functions as a tumor suppressor. Mutations of the Ptch gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly.
Catalog #P3113-82D5
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:1,000
Immunohistochemistry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.25mg/ml
FormSupplied as a liquid in PBS, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide selected from the N-terminal region of human PTCH (KLH).
SpecificityRecognizes human PTCH.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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