Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified B IC

The cytoskeletal adaptor protein Paxillin is found at the interface between actin filaments and the
plasma membrane. Paxillin localizes to focal adhesions, where it provides a platform for the
integration and coordination of adhesion- and growth factor-related signals. Paxillin phosphorylation is required for integrin-mediated cytoskeletal reorganization, and may play a role
in the disassembly of focal adhesions and stress fibers during cellular transformation. Increased
Paxillin protein levels have also been reported in several malignancies, including renal, lung, and
breast carcinomas.
Catalog #	P3113-85C
Applications	Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended Dilution	Western Blot: 1ug/ml
	Immunocytochemistry: 10ug/ml
	Optimal dilutions to be determined by the researcher.
Storage and Stability	Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2b
Clone No	9H169
Host	Mouse
Source	Human
Concentration	~500ug/ml
Form	Supplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
Purity	Purified by Protein G affinity chromatography.
Immunogen	Recombinant human Paxillin, aa59-274; P49023 (E. coli).
Specificity	Recognizes human Paxillin.
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.