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You are here:Home » Antibodies » Abs to Paxillin » Anti -Paxillin

Anti -Paxillin

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IC
The cytoskeletal adaptor protein Paxillin is found at the interface between actin filaments and the
plasma membrane. Paxillin localizes to focal adhesions, where it provides a platform for the
integration and coordination of adhesion- and growth factor-related signals. Paxillin phosphorylation is required for integrin-mediated cytoskeletal reorganization, and may play a role
in the disassembly of focal adhesions and stress fibers during cellular transformation. Increased
Paxillin protein levels have also been reported in several malignancies, including renal, lung, and
breast carcinomas.
Catalog #P3113-85C
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Immunocytochemistry: 10ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9H169
HostMouse
SourceHuman
Concentration~500ug/ml
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution, PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human Paxillin, aa59-274; P49023 (E. coli).
SpecificityRecognizes human Paxillin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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