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PD 98059 (2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one)
PD 98059 (2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one)
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| Potent, selective and cell-permeable inhibitor of MAP kinase kinase | | | (MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself. | | | Catalog # | P3120-50 | | Chemical Name | 2'-Amino-3'methoxyflavone | | Chemical Family | Flavone | | Solubility | Soluble in DMSO. | | Biological Activity | IC50 values for PD 98059-induced effects are in the 1-20uM range for many assays and somewhat weaker in inhibiting cell growth in monolayer or agar for some cells lines. | | Storage and Stability | Lyophilized: Stable for 2 years at-20°C from date of shipment. Store tightly sealed in the dark. | | CAS Number | 167869-21-8 | | Molecular Formula | C16H13NO3 | | Molecular Weight | 267.28 | | Purity | > 99% by HPLC | | Form | Supplied as a lyophilized powder. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | 2'-Amino-3'methoxyflavone |
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