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You are here:Home » Molecular Biology » MB-Protein Kinase Inhibitors » PD 98059 (2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one)

PD 98059 (2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one)

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Specifications

Potent, selective and cell-permeable inhibitor of MAP kinase kinase
(MAPK/ERK kinase or MEK kinase). Inhibits phosphorylation of MAP kinase by MAP kinase kinase. PD 98059 does not inhibit MAP kinase itself.
Catalog #P3120-50
Chemical Name2'-Amino-3'methoxyflavone
Chemical FamilyFlavone
SolubilitySoluble in DMSO.
Biological ActivityIC50 values for PD 98059-induced effects are in the 1-20uM range for many assays and somewhat weaker in inhibiting cell growth in monolayer or agar for some cells lines.
Storage and StabilityLyophilized: Stable for 2 years at-20°C from date of shipment. Store tightly sealed in the dark.
CAS Number167869-21-8
Molecular FormulaC16H13NO3
Molecular Weight267.28
Purity> 99% by HPLC
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names2'-Amino-3'methoxyflavone


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