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You are here:Home » Antibodies » Abs to Enzymes, Isomerase » Anti -PDI (Protein Disulfide Isomerase, Cellular Thyroid Hormone Binding Protein, Disulphide Isomerase, DSI, ERBA2L, Glutathione Insulin Transhydrogenase, GIT, p55, PDIA1, PDIP, PDIR, PHDB, Procollagen-proline 2-oxoglutarate 4-dioxygenase beta, PO4DB, PO4HB, Pr

Anti -PDI (Protein Disulfide Isomerase, Cellular Thyroid Hormone Binding Protein,
Disulphide Isomerase, DSI, ERBA2L, Glutathione Insulin Transhydrogenase, GIT, p55, PDIA1,
PDIP, PDIR, PHDB, Procollagen-proline 2-oxoglutarate 4-dioxygenase beta, PO4DB, PO4HB, Pr

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B IP IH
Protein disulfide isomerase (PDI) is an acidic 55kD thyroid hormone-binding protein that appears to be identical to the glial-p55 protein. It has been suggested to be involved in disulfide-bond formation and isomerization, as well as the reduction of disulfide bonds in proteins. It may also play a role in the thyroid hormone-dependent regulation of actin polymerization and the degradation of the membrane-associated protein type II iodothyronine 5'-deiodinase (5'D-II).
Catalog #P3122-05D
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): 1:100. Antigen retrieval not essential but may optimize staining. Staining in rat intestine yields a pattern consistent with cytoplasmic staining.
Western Blot: 1:1000. Detects a band of ~59kDa representing PDI from rat liver extract or a slightly higher protein at 61kDa representing PDI from human liver extract.
Immunoprecipitation: Inhibits the activity of PDI in vitro.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No9A313
HostMouse
SourceRat
ConcentrationNot Determined
FormSupplied as a liquid, 0.05% sodium azide.
PurityAscites
ImmunogenRecombinant full length rat PDI. Cellular Localization: Endoplasmic reticulum
SpecificityRecognizes rat PDI. Species Crossreactivity: rat and mouse tissues, hamster cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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