Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Enzymes, Isomerase » Anti -PDI (Protein Disulfide Isomerase, Cellular Thyroid Hormone Binding Protein, Disulphide Isomerase, DSI, ERBA2L, Glutathione Insulin Transhydrogenase, GIT, p55, PDIA1, PDIP, PDIR, PHDB, Procollagen-proline 2-oxoglutarate 4-dioxygenase beta, PO4DB, PO4HB, Pr

Anti -PDI (Protein Disulfide Isomerase, Cellular Thyroid Hormone Binding Protein,
Disulphide Isomerase, DSI, ERBA2L, Glutathione Insulin Transhydrogenase, GIT, p55, PDIA1,
PDIP, PDIR, PHDB, Procollagen-proline 2-oxoglutarate 4-dioxygenase beta, PO4DB, PO4HB, Pr

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Protein disulfide isomerase or PDI is an enzyme in the endoplasmic reticulum that catalyzes the formation and breakage of disulfide bonds between cysteine residues within proteins as they fold. This allows proteins to quickly find the correct arrangement of disulfide bonds in their fully folded state and therefore the enzyme acts to catalyze protein folding. Another major function of PDI relates to its activity as a chaperone, in that it aids wrongly folded proteins to reach a correctly folded state without the aid of enzymatic disulfide shuffling. PDI has been found to be involved in the breaking of bonds on the HIV gp120 protein during HIV infection of CD4 positive cells and is required for HIV infection of lymphocytes and monoctyes. Some studies have shown it to be available for HIV infection on the surface of the cell clustered around the CD4 protein yet conflicting studies have shown that it is not available on the cell surface but instead is found in significant amounts in the blood plasma.
Catalog #P3122-05E
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.2, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, C-NLETTKKYAPVD, representing the internal region of the sequence according to NP_006840.2. Homology
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links