Anti -PDX1, NT (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1,
Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor
1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
E B IH |
|
| PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). | | | Catalog # | P3127-05L | | Applications | Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. | | Recommended Dilutions | ELISA: 1:1000 | | Western Blot: 1:100-1:500 | | Immunohistochemistry (Paraffin): 1:10-1:50 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.25mg/ml | | Form | Supplied as a liquid in PBS, 0.09% sodium azide. | | Purity | Purified by Protein A affinity chromatography. | | Immunogen | KLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa47-77 in the N-terminal region of human PDX1. | | Specificity | Recognizes human PDX1. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -PDX1, NT (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1, Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor 1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1) |
External Links
|
