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You are here:Home » Antibodies » Abs to Transcription Factors, Homeobox (HOX) » Anti -PDX1 (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1, Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor 1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)

Anti -PDX1 (Pancreas/Duodenum Homeobox Protein 1, Insulin Promoter Factor 1,
Islet/Duodenum Homeobox-1, Somatostatin-transactivating Factor 1, Insulin Upstream Factor
1, Glucose-sensitive Factor, PDX-1, IPF-1, IDX-1, STF-1, IUF-1, GSF, IPF1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E
PDX1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in the gene encoding PDX1 are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Catalog #P3127-05T
ApplicationsSuitable for use in ELISA. Other applications not tested.
Recommended DilutionELISA: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to C-AAEPEENKRTRTA, from IPF1, at the internal region of the protein (NP_000200.1).
SpecificityRecognizes IPF1. Species sequence homology: Canine, human, mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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