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You are here:Home » Antibodies » Abs to PDZ Domain » Anti -PDZ Domain Containing 1 (CAP70, CLAMP, NHERF3, PDZD1, PDZK1, Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3, NHERF-3, CFTR-associated Protein of 70kD, Na(+)/H(+) Exchanger Regulatory Factor 3, Na/Pi Cotransporter C-terminal-associated Protein 1, NaPi-Cap

Anti -PDZ Domain Containing 1 (CAP70, CLAMP, NHERF3, PDZD1, PDZK1, Na(+)/H(+) Exchange
Regulatory Cofactor NHE-RF3, NHERF-3, CFTR-associated Protein of 70kD, Na(+)/H(+)
Exchanger Regulatory Factor 3, Na/Pi Cotransporter C-terminal-associated Protein 1,
NaPi-Cap

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified B
PDZK1 (PDZ Domain-containing 1; also CFTR-associated protein of 70kD/CAP70) is a 65-70kD member of the NHER (Na/H Exchange Regulator) family of proteins. It is only expressed in epithelium, particularly that found in intestine, kidney and liver. PDZK1 serves as a scaffold protein that connects cell membrane proteins to cytoplasmic regulators. It also serves a critical role in basal-level bicarbonate secretion. Mouse PDZK1 is 519aa in length and contains four PDZ domains (aa9-90; 128-215; 243-323; and 378-458) plus three phosphorylation sites at Ser489, Ser492 and Ser514. Mouse PDZK1 shares 78% and 91% aa identity with human and rat PDZK1, respectively.
Catalog #P3129-80B
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionsWestern Blot: 1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, 0.02% sodium azide. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenE.coli-derived recombinant mouse PDZK1 (rmPDZK1; aa1-519; Accession # Q9JIL4).
SpecificityRecognizes mouse PDZK1. Species Crossreactivity: rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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