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You are here:Home » Antibodies » Abs to PDZ Domain » Anti -PDZK1 (Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3, NHERF-3, CFTR-associated Protein of 70kD, Na(+)/H(+) Exchanger Regulatory Factor 3, Na/Pi Cotransporter C-terminal-associated Protein 1, NaPi-Cap1, PDZ Domain-containing Protein 1, Sodium-hydrogen Ex

Anti -PDZK1 (Na(+)/H(+) Exchange Regulatory Cofactor NHE-RF3, NHERF-3, CFTR-associated
Protein of 70kD, Na(+)/H(+) Exchanger Regulatory Factor 3, Na/Pi Cotransporter
C-terminal-associated Protein 1, NaPi-Cap1, PDZ Domain-containing Protein 1,
Sodium-hydrogen Ex

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na+-dependent inorganic phosphate cotransport therefore playing an important role in tubule function.
Catalog #P3129-80F
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a,k
Clone No1E9
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified by Protein A affinity chromatography.
ImmunogenRecombinant corresponding to aa1-520 from human PDZK1 with GST tag. MW of the GST tag alone is 26kD.
SpecificityRecognizes human PDZK1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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