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Anti -PEDF R (Pigment Epithelial Derived Factor Receptor)
Anti -PEDF R (Pigment Epithelial Derived Factor Receptor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E B |
|
| PEDF R (Pigment epithelium derived factor receptor; also ATGL, PNPLA2 and desnutrin)is a 55kD member of the PNPLA family of proteins. It is expressed in adipocytes, hepatocytes, skeletal muscle, and pigment epithelium. PEDF R specifically hydrolyses triglycerides, releasing long-chain fatty acids. Mouse PEDF R is described as being a 486aa type II transmembrane (TM) protein. Its TM segment is stated to span (aa9-29). Alternatively, it may have a hydrophobic lipid-association domain between (aa267-295). It contains a palatin domain (aa10-179) with a conserved GxSxG enzymatic motif. There are multiple splice forms. Two show alternate start sites at Met57 and Met232, while two others show a deletion of (aa163-196) and (aa253-308), respectively. Over (aa162-253), mouse PEDF R shares 98% and 93% aa identity with rat and human PEDF R, respectively. | | | Catalog # | P3140-04 | | Applications | Suitable for use in Western Blot and Direct ELISA. Other applications not tested. | | Recommended Dilution | Western Blot: 2ug/ml | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Myeloma cells with B cells from Balb/c mice. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | N/A | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 11D53 | | Host | Rat | | Source | Mouse | | Concentration | ~0.5mg/ml (after reconstitition) | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant protein corresponding to aa162-253 from mouse PEDF R expressed in E. coli (Q8BJ56). | | Specificity | Recognizes mouse PEDF R. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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