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You are here:Home » Antibodies » Abs to Enzymes, Protease (Proteinase, Peptidase) » Anti -Pepsinogen I (BSA, Azide, Glycerol Free)

Anti -Pepsinogen I (BSA, Azide, Glycerol Free)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Pepsinogen I, a zymogen, or proenzyme secreted by chief cells in the stomach, is cleaved to form pepsin both in an autocatalytic fashion and by pepsin itself. In humans there are two related forms of pepsin, Pepsinogen I, also known as Pepsinogen A, and Pepsinogen II, also known as Pepsinogen B or progastricsin.
Catalog #P3272-04X
A protein precursor to pepsin, Pepsinogen I or Pepsinogen A is secreted exclusively by the chief cells of the gastric corpus. The levels of Pepsinogen I correlate directly with the active number of chief cells in this area. In cases of severe atrophic gastritis of the corpus region, the chief cells will be destroyed and the levels of Pepsinogen I will fall dramatically.
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
HybridomaProduced by fusion between myeloma cells and BALB/c spleen cells.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No5G18
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS. No preserative added. Available with BSA and sodium azide. See P3272-04.
PurityPurified by Protein G affinity chromatography.
ImmunogenPepsinogen I purified from human tissue
SpecificityRecognizes human Pepsinogen I. No crossreactivity with Pepsinogen II
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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