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You are here:Home » Antibodies » Abs to Enzymes, Protease (Proteinase, Peptidase) » Anti -Pepsinogen II

Anti -Pepsinogen II

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E B IH
Pepsinogen II is a group of precursor molecules for pepsin. These proteins are secreted into the gastric lumen by the pyloric glands of the gastric antrum and also by the chief and neck cells of the gastric corpus (oxyntic mucosa). Negative immunohistochemical reaction for pepsinogen I but positive reaction for pepsinogen II is a typical sign of the antral mucosa and, in the presence of atrophic gastritis, this staining pattern indicates that the positive glands and cells are metaplastic and “pyloric” in differentiation (so called pseudopyloric metaplasia).
Catalog #P3272-06C
ApplicationsSuitable for use in Immunohistochemistry, Western Blot and ELISA. Other applications not tested.
Recommended DilutionImmunohistochemistry: Paraffin
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoL10CC10
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, 1% BSA, 0.09% sodium azide.
PuritySerum
ImmunogenPepsinogen II purified from human tissue
SpecificityRecognizes human Pepsinogen II. Does not crossreact with human Pepsinogen I.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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