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You are here:Home » Antibodies » Abs to Peptides » Anti -Peptide YY (Peptide-YY, PYY, Peptide Tyrosine Tyrosine, GHYY, RATGHYY, Yy)

Anti -Peptide YY (Peptide-YY, PYY, Peptide Tyrosine Tyrosine, GHYY, RATGHYY, Yy)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E IH
Peptide tyrosine-tyrosine (PYY) amide is a 36aa. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.
Catalog #P3285-02B
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionsOptimal dilutions to be determined by the researcher.
Culture MediumRPMI 1640 with 10% fetal calf serum
HybridomaSP2mIL6 myeloma cells with spleen cells from NMRI x BALB/c mice.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone No13A141
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic human PYY
SpecificityRecognizes human PYY.
CrossreactivityNPY or PP in solution, <0.1%
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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