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You are here:Home » Antibodies » Antibodies-Peptides » Anti -Peptide YY (PYY, Peptide Tyrosine Tyrosine)

Anti -Peptide YY (PYY, Peptide Tyrosine Tyrosine)


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Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
Neuropeptide Y (NPY), a neuropeptide colocalized and abundantly released with the neurotransmitter norepinephrine in nervous system, synthesized by postnatal olfactory epithelium of sustentacular cells. It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. NPY, a 97aa peptide in mouse, human (chr 7p15.1) and 98aa in rat has a mol. wt of 11kD. NPY shows sequence homology to Peptide YY (PYY) and over 50% homology in amino acid and nucleotide sequence to Pancreatic Polypeptide (PNP or PPY), all of these homologous peptides have a 36aa mature peptide characterized by a hairpin loop.
PYY: Secreted as 97aa precursor from endocrine cells in the lower small intestine, colon and pancreas. It acts on the gastrointestinal tract as an inhibitor of gastric acid secretion, gastric emptying, and digestive enzyme secretion by the pancreas, and gut motility.
Catalog #P3285-11
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. See catalog #P3285-11A.
Western Blot: 1-10ug/ml using ECL technique.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
FormSupplied as a lyophilized powder from PBS, pH 7.2, 0.1% BSA. Also available without BSA & Azide. See P3285-11B.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, 9aa corresponding to mature peptide region of mouse PYY1 (KLH). Species Sequence Homology: Rat (100%).
SpecificityRecognizes mouse PYY.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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