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P3340-53B Rabbit Anti-Pericentriolar Material 1 Protein (PCM1, PCM-1, hPCM-1, PTC4)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Swiss Prot
Q15154
Isotype
IgG
Grade
Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_006188.3
Shipping Temp
Blue Ice
Storage Temp
-20°C

PCM-1 is required for centrosome assembly and function. This protein is essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. The protein is required to anchor microtubules to the centrosome.

Applications
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide selected from the Center region of human PCM-1 (KLH).
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human PCM-1.
References
1. Balczon R., Bao L.J. Cell Biol. 124:783-793(1994). 2. Corvi R., Berger N.Oncogene 19:4236-4242(2000). 3. Dammermann A., Merdes A.J. Cell Biol. 159:255-266(2002). 4. Reiter A., Walz C.Cancer Res. 65:2662-2667(2005). 5. Murati A., Gelsi-Boyer V.Leukemia 19:1692-1696(2005). 6. Hames R.S., Crookes R.E.Mol. Biol. Cell 16:1711-1724(2005).
USBio References
No references available
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