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You are here:Home » Antibodies » Abs to Peripherin » Anti -Peripherin (PRPH, Neurofilament 4, NEF4)

Anti -Peripherin (PRPH, Neurofilament 4, NEF4)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IC
Peripherin is a type III intermediate filament found initially in sensory neurons of the peripheral nervous system (PNS). It serves as a marker for autonomic and sensory neurons in the PNS and motor neurons in the CNS. Peripherin is a diagnostic marker in amyotrophic lateral sclerosis and certain neuronally-derived tumors. Brain injuries can also trigger expression of peripherin and the formation of peripherin accumulations in neurons that are normally silent for this gene. Peripherin is also expressed in certain neuroendocrine tumors and in the insulin producing cells of the pancreas. Autoantibodies to peripherin are also frequently seen in the sera of patients with diabetes.
Catalog #P3345-01A
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:10,000
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant full length peripherin purified from E. coli
SpecificityRecognizes Peripherin from human, rat, rabbit, cat, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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