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Abs to Peripherin
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Anti -Peripherin (Neurofilament 4, PRPH, NEF4, PRPH1)
Anti -Peripherin (Neurofilament 4, PRPH, NEF4, PRPH1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Supernatant |
B IH IC IF |
|
| Peripherin is a member the intermediate filament protein family which includes desmin, peripherin and vimentin. It is found in neurons of the central nervous system and in sensory neurons of the peripheral nervous system and thus is a useful neuronal-specific marker. Peripherin mRNA can be alternatively spliced, producing 3 proteins having molecular weights of ~56kD (Per-56), ~58kD (Per-58), and ~61kD (Per-61). Antibodies to peripherin can be used in identifying, classifying, and studying neurons throughout the nervous system. Peripherin is also a good marker for the ballooned axons seen in Lou Gehrig's disease and some neuronally derived tumors. Autoantibodies to peripherin are frequently seen in the sera of patients with diabetes. | | | Catalog # | P3345-01J | | Applications | Suitable for use in Immunofluorescence, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. | | Recommended Dilution | Immunofluorescence: 1:500-1:5000 | | Western Blot: 1:500-1:2500 | | Immunohistochemistry (frozen, formalin fixed paraffin embedded): 1:500-1:5000 | | Immunocytochemistry: 1:500-1:5000 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Brain | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 11E315 | | Host | Mouse | | Source | Rat | | Concentration | Not determined. | | Form | Supplied as a liquid, 0.01% thimerosal, 1mg/ml BSA, 50% glycerol. | | Purity | Supernatant | | Immunogen | Recombinant corresponding to rat peripherin. | | Specificity | Recognizes rat Peripherin. Species Crossreactivity: feline, mouse, human. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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