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You are here:Home » Antibodies » Abs to Peripherin » Anti -PRPH (Peripherin, Neurofilament 4, NEF4, PRPH1)

Anti -PRPH (Peripherin, Neurofilament 4, NEF4, PRPH1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH IC
Peripherin is a 57kD Class III intermediate filament subunit found initially in sensory neurons of the peripheral nervous system, which gives the protein its name. Certain sensory neurons in the brain stem express Peripherin normally, as do a few cortical and hippocampal neurons. Interestingly, peripherin protein is upregulated in the lower motor neurons that degenerate in Amyotrophic Lateral Sclerosis (ALS), focusing attention on peripherin as a potential contributory factor to this serious human neurodegenerative disease. Peripherin is also expressed in certain neuroendocrine tumors and in the insulinproducing cells of the pancreas.
Catalog #P3345-01Q
ApplicationsSuitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:10,000
Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant corresponding to human PRPH expressed in E. coli.
SpecificityRecognizes human PRPH. Species Crossreactivity: Rat, rabbit, feline, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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