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You are here:Home » Antibodies » Abs to Enzymes, Peroxiredoxin » Anti -Peroxiredoxin I (Peroxiredoxin-1, Natural Killer Cell-enhancing Factor A, NKEF-A, Proliferation-associated Gene Protein, PAG, Thioredoxin Peroxidase 2, PRDX1, Thioredoxin-dependent Peroxide Reductase 2, PRDX1)

Anti -Peroxiredoxin I (Peroxiredoxin-1, Natural Killer Cell-enhancing Factor A, NKEF-A,
Proliferation-associated Gene Protein, PAG, Thioredoxin Peroxidase 2, PRDX1,
Thioredoxin-dependent Peroxide Reductase 2, PRDX1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites E IP
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation,differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx.Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase(TPx) activity utilizing thioredoxin,thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 30 kilodalton in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
Catalog #P3351-95E
ApplicationsSuitable for use in ELISA and Immunoprecipitation. Other applications not tested.
Recommended DilutionImmunoprecipitation: 1-2ul/400ul lysates
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1, k
Clone No10K304
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in Hepes, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.
PurityAscites
ImmunogenRecombinant human protein purified from E.coli.
SpecificityRecognizes human Peroxiredoxin I.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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