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You are here:Home » Antibodies » Abs to Enzymes, Peroxiredoxin » Anti -Peroxiredoxin 2, CT (PRX2, HGNC:9353, MGC4104, NKEFB, PRP, PRXII, TDPX1, TSA, natural killer-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1, thioredoxin-dependent peroxide reductase 1, torin)

Anti -Peroxiredoxin 2, CT (PRX2, HGNC:9353, MGC4104, NKEFB, PRP, PRXII, TDPX1, TSA,
natural killer-enhancing factor B, thiol-specific antioxidant 1, thioredoxin peroxidase 1,
thioredoxin-dependent peroxide reductase 1, torin)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified
Peroxiredoxin 2 (Prx2), a cytoplasmic antioxidant enzyme and member of the ahpC/TSA family, which acts upon cysteine residues to reduce harmful organic hydroperoxides and hydrogen peroxide, protecting against DNA and protein damage. Prx2 is a predominant thiol protein and is highly expressed in erythrocytes, where it effectively scavenges hydrogen peroxide from glutathione peroxidase and catalase. The influence of Prx2 on oxidative states has been studied in neurological diseases, cancer development and progression, and innate inflammatory responses.
Catalog #P3352-11D
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16000
Western Blot: 0.3-1ug/ml, detects a band of ~20-22kD in human and mouse brain cell lysates.
Optimal dilution determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in TBS, pH7.3, 0.02% sodium azide and 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide C-NVDDSKEYFSKHN corresponding to the C-terminal region of Peroxiredoxin 2 isoform a and isoform b.
SpecificityRecognizes an epitope within the C-terminal (CT) region of peroxiredoxin 2 (Prx2).
Species CrossreactivityMouse. Based on sequence similarity, is expected to react with rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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