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You are here:Home » Antibodies » Abs to Enzymes, Peroxiredoxin » Anti -PRDX2 (Peroxiredoxin 2, Prx2, Peroxiredoxin-2, Natural Killer Cell-enhancing Factor B, NKEF-B, PRP, Thiol-specific Antioxidant Protein, TSA, Thioredoxin Peroxidase 1, Thioredoxin-dependent Peroxide Reductase 1, NKEFB, TDPX1)

Anti -PRDX2 (Peroxiredoxin 2, Prx2, Peroxiredoxin-2, Natural Killer Cell-enhancing Factor
B, NKEF-B, PRP, Thiol-specific Antioxidant Protein, TSA, Thioredoxin Peroxidase 1,
Thioredoxin-dependent Peroxide Reductase 1, NKEFB, TDPX1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the aa sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30kD in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol.
Catalog #P3352-12K
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b, k
Clone No13A12
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.
PurityAscites
ImmunogenRecombinant corresponding to human Peroxiredoxin 2 expressed in E.coli.
SpecificityRecognizes human Peroxiredoxin 2. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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