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You are here:Home » Antibodies » Abs to Obesity Proteins » Anti -PGC-1 alpha (Peroxisome Proliferator Activated Receptor gamma Coactivator 1 alpha, PPAR gamma Coactivator 1 alpha, PPARGC-1 alpha, PPARGC1A, PGC1 alpha, PGC1A, PGC1, PGC-1, Ligand Effect Modulator 6, LEM6)

Anti -PGC-1 alpha (Peroxisome Proliferator Activated Receptor gamma Coactivator 1 alpha,
PPAR gamma Coactivator 1 alpha, PPARGC-1 alpha, PPARGC1A, PGC1 alpha, PGC1A, PGC1, PGC-1,
Ligand Effect Modulator 6, LEM6)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH IC
The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.
Catalog #P3363-03
ApplicationsSuitable for use in Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionsImmunohistochemistry (Paraffin): 1:100-1:500
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in TBS, 0.1% BSA, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to a region between residues 250 and 300 of human peroxisome proliferative activated receptor, gamma, coactivator 1, alpha using the numbering given in SwissProt entry Q9UBK2 (GeneID 10891).
SpecificityRecognizes human PGC-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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