Anti -Peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1A, coactivator 1 alpha LEM6, Ligand effect modulator 6,PGC1, PGC-1(alpha), PGC1A, PGC-1-alpha, PGC-1v, PPAR gamma coactivator 1-alpha, PPARGC1, PPARGC-1-alpha)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
B |
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| PGC1 beta (peroxisome proliferator-activated receptor gamma coactivator 1 beta), also known as PPARGC1B, is an 110kD protein that belongs to a family of PPAR coactivators. It coactivates nuclear receptors such as ERRalpha, upregulating expression of proteins that promote mitochondrial fusion and control basal mitochondrial biogenesis. N- and C-terminal alternate sequences, or deletion of aa156-194, produce isoforms of 984, 1017, 1023 (most common) and 1055aa. Human PGC1 beta aa315-420, which is common to all isoforms, shares 79% and 76% aa identity with mouse and rat PGC1 beta, respectively. | | | Catalog # | P3363-05 | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 0.2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in 0.2um sterile-filtered solution PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Recombinant human PGC1 beta aa315-420; Q86YN6 (E. coli). | | Specificity | Recognizes human/mouse PGC1 beta at ~95kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1A, coactivator 1 alpha LEM6, Ligand effect modulator 6,PGC1, PGC-1(alpha), PGC1A, PGC-1-alpha, PGC-1v, PPAR gamma coactivator 1-alpha, PPARGC1, PPARGC-1-alpha) |
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