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You are here:Home » Antibodies » Abs to Multi Drug Resistance (MDR) » Anti -P-Glycoprotein (p170, Pgp, MDR Protein, Multi Drug Resistance Associated Protein)

Anti -P-Glycoprotein (p170, Pgp, MDR Protein, Multi Drug Resistance Associated Protein)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Multi-drug resistance (MDR) associated p-Glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble p- Glycoprotein is detected in extracellular fluids of cancer patients, such as malignant ascites and serum. The Mr of soluble p-Glycoprotein is the same as that of membrane bound p-Glycoprotein.
Catalog #P3365-05
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml for 2h at RT
Optimal dilutions to be determined by the researcher.
Positive ControlBreast carcinoma, T47D cells
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
CAS Numbern/a
Clone TypePolyclonal
IsotypeIgG2a,k
HostRabbit
SourceHuman
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminus of human p-Glycoprotein.
SpecificityRecognizes human p-Glycoprotein.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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