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You are here:Home » Antibodies » Abs to Enzymes, Phosphodiesterase » Anti -PDE3B (Phosphodiesterase 3B)

Anti -PDE3B (Phosphodiesterase 3B)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B. Phosphodiesterases (PDE) are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. PDE3B has two splice variants that are expressed in adipocyte tissue, hepatocyte, kidney, spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity.
Catalog #P4072-02S
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide surrounding aa 948 of mouse PDE3B.
SpecificityRecognizes mouse PDE3B. Species crossreactivity: mouse, rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPDE3B, phosphodiesterase type-3


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