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You are here:Home » Antibodies » Abs to Enzymes, Phosphodiesterase » Anti -Phosphodiesterase 4B (PDE4B, PDEIVB, cAMP-specific 3',5'-cyclic Phosphodiesterase 4B, DPDE4, PDE32)

Anti -Phosphodiesterase 4B (PDE4B, PDEIVB, cAMP-specific 3',5'-cyclic Phosphodiesterase
4B, DPDE4, PDE32)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. Cyclic nucleotides are important second messengers that regulate and mediate a number of cellular responses to extracellular signals, such as hormones, light, and neurotransmitters. The cyclic nucleotide phosphodiesterases (PDEs) regulate the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. This gene encodes a protein that specifically hydrolyzes cAMP. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Catalog #P4072-03S
Positive Control Mouse Brain Lysate
ApplicationsSuitable for use in ELISA (peptide) and Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH 7.2. 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: C-DIDIATEDKSPVDT, representing the C Terminus of the human protein according to NP_002591.2; NP_001032418.1; NP_001032416.1; NP_001032417.1.
SpecificityThis antibody is expected to recognize all reported isoforms (NP_002591.2, NP_001032418.1, NP_001032416.1 and NP_001032417.1). Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesPhosphodiesterase 4B, cAMP-specific, DKFZp686F2182, EC=3.1.4.17, MGC126529, PDE4B5


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