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You are here:Home » Antibodies » Abs to Enzymes, Phosphodiesterase » Anti -Phosphodiesterase 10A (PDE10A, cAMP and cAMP-inhibited cGMP 3'5'-cyclic Phosphodiesterase 10A, FLJ11894, HSPDE10A, Phosphodiesterase 10A1)

Anti -Phosphodiesterase 10A (PDE10A, cAMP and cAMP-inhibited cGMP 3'5'-cyclic
Phosphodiesterase 10A, FLJ11894, HSPDE10A, Phosphodiesterase 10A1)

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Specifications

Clone Host Grade Applications
Rabbit Affinity Purified B IP IH IF
One of the many phosphodiesterases that compartmentalize and hydrolyze cAMP and cGMP into AMP and GMP is PDE10. Only one member of the cAMP and cGMP-specific PDE10 family has been cloned and characterized. The PDE10A gene is expressed in at least two variant forms (PDE10A1, PDE10A2) generated by RNA splicing and/or the use of alternate initiation sites. PDE10A is widely expressed in the putamen and caudate nucleus in the brain, thyroid and testis. The expression of PDE10A is also abundant in Heart.
Catalog #P4072-10B
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunoprecipitation: 1:250
Western Blot: 1:1500 detects a band at ~90-93kD in rat brain and rat pancreas samples
Immunohistochemistry: paraffin sections
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone Type


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