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You are here:Home » Antibodies » Abs to Enzymes, Phospholipase » Anti -Phospholipase A2, Secretory, Group III (Group III Secretory Phospholipase A2, GIII sPLA2, GIII-SPLA2, Group 3 Secretory Phospholipase A2, Phosphatidylcholine 2-acylhydrolase 3, PLA2G3, SPLA2III, sPLA2-III)

Anti -Phospholipase A2, Secretory, Group III (Group III Secretory Phospholipase A2, GIII
sPLA2, GIII-SPLA2, Group 3 Secretory Phospholipase A2, Phosphatidylcholine 2-acylhydrolase
3, PLA2G3, SPLA2III, sPLA2-III)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
Human group III secreted phospholipase A2 belongs to a superfamily of intracellular and secreted enzymes that catalyze the hydrolysis of glycerophospholipids at the sn-2 position to release fatty acids and lysophospholipids. Group III PLA2 enzymes were originally identified in invertebrates such as bees and scorpions. human group III sPLA2 has been shown to be a calcium dependent enzyme. It consists of a central group III sPLA2 domain flanked by unique N- and C-terminal domains that are proteolytically removed in most tissues. The sPLA2 domain is sufficient for catalytic activity. SPLA2-III is preferentially expressed in the microvascular endothelium of tissues with inflammation, ischemic injury and cancer.
Catalog #P4074-06G8
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman colon carcinoma
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the internal domain of human PLA2G3.
SpecificityRecognizes human PLA2G3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesEC=3.1.1.4


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